Publications
Que Lab Publications (University of Texas at Austin)
Price, S.; Mehta, R.; Tan, D.; Hinojosa, A.; Thomas, P. W.; Cummings, T.; Fast, W.; Que, E. L. "Structural insights into the design of reversible fluorescent probes for metallo-B-lactamases NDM-1, VIM-2, and IMP-1." J. Inorg. Biochem. 2022, 233, 111869. Link King, T. L.; Palomero, O. E.; Grimes, D. A.; Goralski, S. T.; Jones, R. A.; Que, E. L. "Modulating extraction and retention of fluorinated B-diketonate metal complexes in perfluorocarbons through the use of non-fluorinated neutral ligands." Inorg. Chem. Front., 2021, 8 (20), 4488-4496. Link Mehta, R.; Rivera, D. D.; Reilley, D. J.; Tan, D.; Thomas, P. W.; Hinojosa, A.; Stewart, A. C.; Cheng, Z.; Thomas, C. A.; Crowder, M. W.; Alexandrova, A. N.; Fast, W.; Que, E. L. "Visualizing the Dynamic Metalation State of New Delhi Metallo-β-lactamase-1 in Bacteria Using a Reversible Fluorescent Probe." J. Am. Chem. Soc., 2021. Link Spotlighted on JACS Recent Publications and C&EN! Prosser, K. E.; Xie, D.; Chu, A.; MacNeil, G. A.; Varju, B. R.; Kadakia, R. T.; Que, E. L.; Walsby, C. J. "Copper(II) Pyridyl Amino‐Phenolates: Hypoxia‐Selective, Nucleus Targeting Cytotoxins, and Magnetic Resonance Probes." Chem. Eur. J., 2021. Link King, T. L.; Palomero, O. E.; Bard, A. B.; Espinoza Jr., J. A.; Guo, H.; Schipper, D.; Yang, X.; DePue, L. J.; Que, E. L.; Jones, R. A. "Visible luminscence Ln42 nanotorus coordination clusters." J. Coord. Chem., 2020, 74, 92-101. Link Xie, D.; Yu, M.; Xie, Z.; Kadakia, R. T.; Chung, C.; Ohman, L. E.; Javanmardi, K.; Que, E. L. "Versatile Nickel (II) Scaffolds as Coordination-Induced Spin-State Switches for 19F Magnetic Resonance-Based Detection." Angew. Chem. Int. Ed., 2020, 59, 2-10. Link This article is also featured in Hot Topic: Fluorine Chemistry! Kadakia, R. T.;* Xie, D:* Guo, H; Bouley, B. S.; Yu, M.; Que, E. L. "Responsive fluorinated nanoemulsions for 19F magnetic resonance detection of cellular hypoxia." Dalton Trans., 2020, 49, 16419-16424. Link Part of Dalton Trans. themed collection: New Talent: Americas! Aggarwal, K.; Kuka, T. P.; Banik, M.; Medellin, B. P.; Ngo, C. Q.; Xie, D.; Fernandes, Y.; Dangerfield, T. L.; Ye, E.; Bouley, B.; Johnson, K. A.; Zhang, Y. J.; Eberhart, J. K.; Que, E. L. "Visible Light Mediated Bidirectional Control Over Carbonic Anhydrase Activity in Cells and in vivo Using Azobenzene Sulfonamides." J. Am. Chem. Soc., 2020, 142, 14522-14531. Link Yu, M.; Xie, D.; Kadakia, R. T.; Wang, W.; Que, E. L. "Harnessing Chemical Exchange: 19F Magnetic Resonance OFF/ON Zinc Sensing with A Tm(III) Complex." Chem. Commun., 2020, 56, 6257-6260. Link He, J.; Aggarwal, K.; Katyal, N.; He, S.; Chiang, E.; Dunning, S. G.; Reynolds III, J. E.; Steiner, A.; Henkelman, G.; Que, E. L.; Humphrey, S. M. "Reversible Solid-State Isomerism of Azobenzene-Loaded Large-Pore Isoreticular Mg-CUK-1." J. Am. Chem. Soc., 2020, 142, 6467-6471. Link Xie, D.;* Yu, M.;* Kadakia, R. T.; Que, E. L. "19F Magnetic Resonance Activity-Based Sensing Using Paramagnetic Metals." Acc. Chem. Res., 2020, 53, 2-10. Link Kadakia, R. T.; Xie, D.; Martinez Jr, D.; Yu, M.; Que, E. L. "A dual-responsive probe for detecting cellular hypoxia using 19F magnetic resonance and fluorescence." Chem. Commum., 2019, 55, 8860-8863. Link Part of Chem. Commun. themed collection: 2019 Emerging Investigators! Yu, M.; Bouley, B. S.; Xie, D.; Que, E. L. "Highly fluorinated metal complexes as dual 19F and PARACEST imaging agents," Dalton Trans., 2019, 48, 9337-9341. Link Fikes, A. G.; Aggarwal, K.; Que, E. L. "Glutathione-Mediated Activation of a Disulfide Containing Fe3+ Complex," Inorganica Chimica Acta, 2019, 490, 139-143. Link Ngo, C.; Mehta, R.; Aggarwal, K.; Fikes, A.; Greer, S.; Que, E. L. "Pull-down of metallated carbonic anhydrase using desthiobiotin-based probes," ChemBioChem, 2019, 20, 1003-1007.. Link Aggarwal, K.; Banik, M.; Medellin, B.; Que, E. L."In Situ Photoregulation of Carbonic Anhydrase Activity Using Azobenzenesulfonamides," Biochemistry, 2019, 58, 48-53. Link Enriquez, J. S.; Yu, M.; Bouley, B. S.; Xie, D.; Que, E. L. "Copper(II) complexes for cysteine detection using 19F magnetic resonance," Dalton Trans., 2018, 47, 15024-15030. Link Xie, D.; Ohman, L. E.; Que, E. L. "Toward Ni(II) complexes with spin switches for 19F MR-based pH sensing," Magn. Reson. Mater. Phy. 2018. Link Yu, M.; Bouley, B. S.; Xie, D.; Enriquez, J. S.; Que, E. L. "19F PARASHIFT Probes for Magnetic Resonance Detection of H2O2 and Peroxidase Activity," J. Am. Chem. Soc. 2018, 140, 10546-10552. Link Selected to be a part of JACS 2019 Young Investigators Virtual Issue! Mehta, R.; Qureshi, M.H.; Purchal, M.K.; Greer, S.M.; Gong, S.; Ngo, C.; Que, E.L. "A new probe for detecting zinc-bound carbonic anhydrase in cell lysates and cells," Chem Commun. 2018, 54, 5442-5445. Link Xie, D.; Kim, S.; Kohli, V.; Banerjee, A.; Yu, M.; Enriquez, J.S.; Luci, J.J.; Que, E.L. "Hypoxia-Responsive 19F MRI Probes with Improved Redox Properties and Biocompatibility," Inorg. Chem. 2017, 56, 6429-6437. Link Yu, M.; Xie, D.; Phan, K.P.; Enriquez, J.S.; Luci, J.J.; Que, E.L. "A Co(II) complex for 19F MRI-based detection of reactive oxygen species," Chem. Commun. 2016, 52, 13885-13888. Link Yang, X.; Wang, S.; Schipper, D.; Zhang, L.; Li, Z.; Huang, S.; Yuan, D.; Chen, Z.; Gnanam, A.J.; Hall, J.W.; King, T.L.; Que, E.L.; Dieye, Y.; Vadivelu, J.; Brown, K.A.; Jones R.A. "Self-assembly of high-nuclearity lanthanide-based nanoclusters for potential bioimaging applications," Nanoscale, 2016, 8, 11123-9. Link Xie, D.; King, T.L.; Banerjee, A.; Kohli, V.; Que, E.L. "Exploiting copper redox for 19F magnetic resonance-based detection of cellular hypoxia," J. Am. Chem. Soc. 2016 , 138, 2937-40. Link --- Post-doctoral publications (O'Halloran/Woodruff Labs, Northwestern University) Que, E.L.; Duncan, F.E.; Bayer, A.R.; Philips, S.J.; Roth, E.W.; Bleher, R.; Gleber, S.C.; Vogt, S.; Woodruff, T.K.; O'Halloran, T.V. "Zinc sparks induce physiochemical changes in the egg zona pellucida that prevent polyspermy," Integr. Biol. 2017, 9, 135-144. Link Featured as the inside cover for the Feb 2017 issue. Duncan, F.E.*; Que, E.L.*; Zhang, N.*; Feinberg, E.C.; O'Halloran, T.V.; Woodruff, T.K. "The zinc spark is an inorganic signature of human egg activation," Sci. Rep., 2016, 6, 24737. *co-first authors Link Highlighted by a number of news outlets. Zhang, N.; Duncan, F.E.; Que, E.L.; O'Halloran, T.V.; Woodruff, T.K. "The fertilization-induced zinc spark is a novel biomarker of mouse embryo quality and early development," Sci. Rep. 2016, 6, 22772. Link Kong, B.Y.; Duncan, F.E.; Que, E.L.; Xu, Y.; Vogt, S.; O'Halloran, T.V.; Woodruff, T.K. "The inorganic anatomy of the mammalian preimplantation embryo and the requirement of zinc during the first mitotic divisions," Dev. Dyn. 2015, 244, 935-47. Link Que, E.L.; Bleher, R.; Duncan, F.E.; Kong, B.Y.; Gleber, S.C.; Vogt, S.; Chen, S.; Garwin, S.A.; Bayer, A.R.; Dravid, V.P.; Woodruff, T.K.; O'Halloran, T.V. "Quantitative mapping of zinc fluxes in the mammalian egg reveals the origin of fertilization-induced zinc sparks," Nature Chem. 2015, 7, 130-139. doi:10.1038/nchem.2133. Link Highlighted by a number of news outlets including C&EN News, Huffington Post, Slate, NPR's Science Friday Picture of the Week, and television stations (WGN, Fox). Original press release from Northwestern University. Kong, B.Y.; Duncan, F.E.; Que, E.L.; Kim, A.M.; O'Halloran, T.V.; Woodruff, T.K. "Maternally-derived zinc transporters ZIP6 and ZIP10 drive the mammalian oocyte-to-egg transition," Mol. Hum. Reprod. 2014, 20, 1077-1089. Link Ya, R.; Que, E.L.; O'Halloran, T.V.; Woodruff, T.K. "Zinc as a key meiotic cell-cycle regulator in the mammalian oocyte," In Zinc Signals in Cellular Functions and Disorders. Fukada, T., Kambe, T., Eds; Springer: Japan, 2014, 315-343. Link Yong, Y.P.; Gleber, S.C.; O'Halloran, T.V.; Que, E.L.; Bleher, R.; Vogt, S.; Woodruff, T.K.; Jacobsen, C. "Low-dose X-ray fluorescence tomography images using differential phase contrast," J. Synchrotron Radiat. 2014, 21, 229-234. Link Marvin, R. G.; Wolford, J. L.; Kidd, M. J.; Murphy, S.; Ward, J.; Que, E. L.; Mayer, M. L.; Penner-Hahn, J. E.; Jaldar, K.; O’Halloran, T. V. “Fluxes in ‘Free’ and Total Zinc are Essential for Progression of Intraerythrocytic Stages of Plasmodium falciparum,” Chem. Biol. 2012, 19, 731-741. PMCID: PMC3601789 Link --- PhD publications (Chang lab, University of California, Berkeley) Que, E. L.; New, E. J.; Chang, C. J. “A Cell-Permeable Gadolinium Contrast Agent for Magnetic Resonance Imaging of Copper in a Menkes Disease Model,” Chem. Sci. 2012, 3, 1829-1834. Link Que, E. L.; Chang, C. J. “Responsive Magnetic Resonance Imaging Contrast Agents as Chemical Sensors for Metals in Biology and Medicine,” Chem. Soc. Rev. 2010, 39, 51-60. Link Que, E. L.; Gianolio, E.; Baker, S. L.; Aime, S.; Chang, C.J. “A Copper-Activated Magnetic Resonance Imaging Contrast Agent with Improved Turn-On Relaxivity Response and Anion Compatibility,” Dalton Trans. 2010, 39, 469-476. Link Que, E. L.; Gianolio, E.; Baker, S. L.; Wong, A. P.; Aime, S.; Chang, C.J. “Copper Responsive Magnetic Resonance Imaging Contrast Agents,” J. Am. Chem. Soc. 2009, 131, 8527-8536. Link Que, E. L.; Domaille, D. W.; Chang, C. J. "Metals in Neurobiology: Probing Their Chemistry and Biology with Molecular Imaging," Chem. Rev. 2008, 108, 1517-1549. Link Domaille, D. W.; Que, E. L.; Chang, C. J. "Synthetic Fluorescent Sensors for Studying the Cell Biology of Metals," Nat. Chem. Biol. 2008, 4, 168-175. Link Que, E. L.; Chang, C. J. "A Smart Magnetic Resonance Contrast Agent for Selective Copper Sensing," J. Am. Chem. Soc. 2006, 128, 15942-15943. Link --- Chastek, T.T.; Que, E.L.; Jarzombeck, P.; Macosko, C.W.; Stein, A. "Synthesis of lamellar isobutyl silicates and dispersion in polypropylene melts," J. Appl. Polymer Sci. 2007, 105, 1456-1465. Link Jensen, M.P.; Que, E.L.; Shan, X.; Rybak-Akimova, E.; Que, L. Jr. "Spectroscopic and kinetic studies of the reaction of [Cu(I)(6-PhTPA)]+ with O2," Dalton Trans. 2006, 29, 3523-3527. Link Chastek, T.T.; Que, E.L.; Shore, J.S.; Lowy, R.J. III; Macosko, C.; Stein, A. "Hexadecyl-functionalized lamellar mesostructured silicates and aluminosilicates designed for polymer-clay nanocomposites. Part I. Clay synthesis and structure," Polymer, 2005, 46, 4421-4430. Link Jensen, M.P.; Lange, S.J.; Mehn, M.P.; Que, E.L.; Que, L. Jr. "Biomimetic aryl hydroxylation derived from alkyl hydroperoxide at a nonheme iron center. Evidence for an Fe(IV)=O oxidant," J. Am. Chem. Soc. 2003, 125, 2113-2128. Link |
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